Excitation-contraction coupling in heart
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W. J. Lederer; M. B. Cannell; N. M. Cohen; J. R. Berlin
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Article
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1989
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Springer
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English
⚖ 381 KB
We have investigated the links between electrical excitation and contraction in mammalian heart muscle. Using isolated single cells from adult rat ventricle, a whole-cell voltage-clamp technique and quantitative fluorescence microscopy, we have measured simultaneously calcium current (ICa) and [Ca2+