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CA 125 in the monitoring of response to chemotherapy of ovarian carcinoma

✍ Scribed by M. Quaranta; V. Lorusso; M. Coviello; G. Micelli; A. Casamassima

Publisher
John Wiley and Sons
Year
1988
Tongue
French
Weight
225 KB
Volume
41
Category
Article
ISSN
0020-7136

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✦ Synopsis

CA 125 serum levels were assessed in 23 patients undergoing chemotherapy for advanced epithelial ovarian carcinoma (EOC). Rising, falling and unchanged levels correlated with disease in 21 out of 23 (95%) cases. Ten out of I I patients who showed objective response to chemotherapy had a decrease in antigen levels. Two out of 3 patients with stable disease had unchanged values. Progression was always associated with rising levels. CA 125 is a reliable marker for monitoring response to chemotherapy in advanced epithelial ovarian carcinoma.

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Plasma D-dimer and peritoneal CA-125 lev
Plasma D-dimer and peritoneal CA-125 levels as predictors of disease status in ovarian carcinoma
✍ Peter G. Rose; Jill M. Terrien; Stephen Baker πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 429 KB

## Abstract Although serum CA‐125 has improved our ability to monitor tumor response in ovarian carcinoma, ∼50% of patients with normalization of CA‐125 have persistent disease at second look laparotomy. Peritoneal CA‐125 and plasma D‐Dimer levels were studied to determine if their use could increa