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C3. Mechanisms of human colon cancer cells sensitization to nitric oxide-induced apoptosis

โœ Scribed by M. Cortier; J.F. Jeannin; A. Bettaieb


Book ID
116790402
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
67 KB
Volume
17
Category
Article
ISSN
1089-8603

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Nitric oxide suppresses apoptosis in hum
โœ Uwe Wenzel; Sabine Kuntz; Ulrike Jambor de Sousa; Hannelore Daniel ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 880 KB

## Abstract In cells lacking a functional p53 tumor suppressor protein, the endogenous free radical nitric oxide (NO) appears to inhibit apoptosis, and thereby promotes growth of cancer cells. In order to elucidate the underlying mechanisms on a molecular basis, we used HTโ€29 human colon carcinoma