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C-wave versus electrooculogram in diseases of the retinal pigment epithelium

✍ Scribed by J. Röver; M. Bach

Publisher
Springer-Verlag
Year
1987
Tongue
English
Weight
303 KB
Volume
65
Category
Article
ISSN
0012-4486

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✦ Synopsis

The c-wave and the electrooculogram (EOG) are retinal potentials predominantly generated by the pigment epithelium. In most diseases both parameters show a parallel decrease in amplitude. However, in patients with dominant drusen, and cone dystrophies, and in clinically nonaffected members of families suffering from vitelliform maeula degeneration, the EOG is close to normal whereas the c-wave shows a reduced amplitude. These findings suggest a higher sensitivity of the generators of the c-wave compared with those responsible for the EOG. Thus the direct current electroretinogram provides additional diagnostic information.

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