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Hyperpigmented lesions of the retinal pigment epithelium in familial adenomatous polyposis

✍ Scribed by Baker, Richard H. ;Heinemann, M.-H. ;Miller, Helen H. ;DeCosse, Jerome J. ;Opitz, John M. ;Reynolds, James F.

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
580 KB
Volume
31
Category
Article
ISSN
0148-7299

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## Development of one hundred or more adenomas in the colon and rectum is diagnostic for the dominantly inherited, autosomal disease Familial Adenomatous Polyposis (FAP). It is possible to identify a mutation in the Adenomatous Polyposis Coli (APC) gene in approximately 80% of the patients, and alm