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C-reactive protein (CRP) increases VEGF-A expression in monocytic cells via a PI3-kinase and ERK 1/2 signaling dependent pathway

✍ Scribed by Gaëlle Bello; Frédéric Cailotto; Didier Hanriot; Marie-Nathalie Kolopp-Sarda; Véronique Latger-Cannard; Ketsia Hess; Faiez Zannad; Dan Longrois; Armelle Ropars

Book ID: 118421994
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 549 KB
Volume: 200
Category: Article
ISSN: 0021-9150
DOI: 10.1016/j.atherosclerosis.2007.12.046

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## Abstract Cells typically die by either apoptosis or necrosis. However, the consequences of apoptosis and necrosis are quite different for a whole organism. In the case of apoptosis, the cell content remains packed in the apoptotic bodies that are removed by marcrophages, and thereby inflammation