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YC-1 increases cyclo-oxygenase-2 expression through protein kinase G- and p44/42 mitogen-activated protein kinase-dependent pathways in A549 cells

โœ Scribed by Ming-Shyan Chang; Wen-Sen Lee; Che-Ming Teng; Horng-Mo Lee; Joen-Rong Sheu; George Hsiao; Chien-Huang Lin


Book ID
110007350
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
320 KB
Volume
136
Category
Article
ISSN
0007-1188

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Basic calcium phosphate crystal inductio
โœ Michele A. Brogley; Marcella Cruz; Herman S. Cheung ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 237 KB ๐Ÿ‘ 1 views

Synovial fluid basic calcium phosphate (BCP) crystals are markers of severe joint degeneration in osteoarthritis. These crystals are mitogenic and induce protooncogene expression and matrix metalloproteinase (MMP) synthesis and secretion in human fibroblasts, effects that are specifically blocked by