Basic calcium phosphate crystal inductio
โ
Michele A. Brogley; Marcella Cruz; Herman S. Cheung
๐
Article
๐
1999
๐
John Wiley and Sons
๐
English
โ 237 KB
๐ 1 views
Synovial fluid basic calcium phosphate (BCP) crystals are markers of severe joint degeneration in osteoarthritis. These crystals are mitogenic and induce protooncogene expression and matrix metalloproteinase (MMP) synthesis and secretion in human fibroblasts, effects that are specifically blocked by