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c-Myc inhibits TP53INP1 expression via promoter methylation in esophageal carcinoma

✍ Scribed by Wenhao Weng; Qinyuan Yang; Miaolong Huang; Yongxia Qiao; Yuan Xie; Yongchun Yu; An jing; Zhi Li

Book ID
116301323
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
883 KB
Volume
405
Category
Article
ISSN
0006-291X

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## Abstract Overexpression of cyclooxygenase‐2 (COX‐2) and elevation of its derivative prostaglandin E~2~ (PGE~2~) are implicated in human esophageal squamous cell carcinoma. The expression of c‐Myc, an oncogenic transcription factor, is also upregulated in this malignant disease. This study sought