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C-kit protein expression correlated with activating mutations in KIT gene in oral mucosal melanoma

✍ Scribed by Rosario S. Rivera; Hitoshi Nagatsuka; Mehmet Gunduz; Beyhan Cengiz; Esra Gunduz; Chong Huat Siar; Hidetsugu Tsujigiwa; Ryo Tamamura; Kok Ng Han; Noriyuki Nagai

Book ID
106117876
Publisher
Springer
Year
2007
Tongue
English
Weight
279 KB
Volume
452
Category
Article
ISSN
1432-2307

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## Abstract Activating mutations in either __BRAF__ or __NRAS__ are seen in a significant number of malignant melanomas, but their incidence appears to be dependent to ultraviolet light exposure. Thus, __BRAF__ mutations have the highest incidence in non‐chronic sun damaged (CSD), and are uncommon