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c-kit point mutation of extracellular domain in patients with myeloproliferative disorders

โœ Scribed by Yoshio Nakata; Akiro Kimura; Osamd Katoh; Kuniko Kawaishi; Hideo Hyodo; Kazuhiro Abe; Atsushi Kuramoto; Yukio Satow


Book ID
114714309
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
326 KB
Volume
91
Category
Article
ISSN
0007-1048

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Correlations of JAK2โ€“V617F mutation with
โœ Matthaios Speletas; Eirini Katodritou; Chrisoula Daiou; Eudokia Mandala; Emmanou ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 212 KB

Recently, the acquired mutation JAK2-V617F has been described in the majority of patients with myeloproliferative disorders (MPDs). In this study we evaluated its clinical and laboratory correlates in 166 patients with MPDs. The mutation was detected by allele-specific PCR in 119 patients: 81.4% (35