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c-Kit-negative fibroblast-like cells express platelet-derived growth factor receptor α in the murine gastrointestinal musculature

✍ Scribed by Satoshi Iino; Kazuhide Horiguchi; Satomi Horiguchi; Yoshiaki Nojyo


Book ID
106100184
Publisher
Springer
Year
2009
Tongue
English
Weight
920 KB
Volume
131
Category
Article
ISSN
1432-119X

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## Abstract ## BACKGROUND Gastrointestinal stromal tumors (GISTs) are noncomplex sarcomas that often are due to __c‐kit__‐activating and platelet‐derived growth factor receptor α gene (__PDGFRα__)‐activating mutations and perturbations of their related signaling pathways. Molecular and cytogenetic