c-erbB-2/neu protein expression, DNA ploidy and S phase in breast cancer
β Scribed by R. Dittadi; F. Calderazzo; A. Cabrelle; S. Di Fresco; M. Gion; L. Chieco-Bianchi
- Book ID
- 114716103
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 609 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0960-7722
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Expression of c-erbB-2 protein has been associated with poor prognosis and poor response to chemotherapy in breast cancer patients. In the present prospective study, we have analyzed whether c-erbB-2, p53 and P170 proteins may be determinants of tumor resistance in locally advanced breast cancer pat
## Abstract Strong expression of human epidermal growth factor receptor 2 (HERβ2)/neu in breast cancer has been associated with poor prognosis. Reduced expression of p27^Kip1^, a cyclinβdependent kinase inhibitor, correlates with poor clinical outcome in breast cancer. In this study, we provide a c