C-erbB-2 protein in the sera of breast cancer patients
β Scribed by Tatsuhiko Narita; Hiroomi Funahashi; Yasuyuki Satoh; Hiroshi Takagi
- Publisher
- Springer US
- Year
- 1992
- Tongue
- English
- Weight
- 530 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0167-6806
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Expression of c-erbB-2 protein has been associated with poor prognosis and poor response to chemotherapy in breast cancer patients. In the present prospective study, we have analyzed whether c-erbB-2, p53 and P170 proteins may be determinants of tumor resistance in locally advanced breast cancer pat
## Abstract Fifty fineβneedle aspiration cytologies of breast that were diagnosed as carcinomas were retrieved from the files and retrospectively evaluated for the expression of __c__β__erb__Bβ2 oncoprotein using standard immunocytochemical methods. Corresponding histologic sections of all tumors w
The immunohistochemical expression of p53 and c-erbB-2 gene proteins was examined in a series of 130 breast adenocarcinomas. This study intended to investigate whether the frequency of the altered expression of the tumour suppressor gene p53 and the overexpression of the oncogene c-erbB-2 in breast