C-erbB-2 overexpression in primary breast cancer: independent prognostic factor in patients at high risk
✍ Scribed by I. Schönborn; W. Zschiesche; E. Spitzer; C. Minguillon; M. Möhner; K. Ebeling; R. Grosse
- Publisher
- Springer US
- Year
- 1994
- Tongue
- English
- Weight
- 688 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0167-6806
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Background and Objectives: We investigated whether expression levels of c-erbB-2 and p53 proteins in breast cancer tissues differ in primary and metastatic lesions. Methods: Immunohistochemical staining or sandwich enzyme immunoassay was used to determine expression levels of c-erbB-2 and p53 protei
The relationship was assessed between c-erbB-2 oncoprotein expression and other prognostic factors in breast cancer, such as axillary and internal mammary node metastases. The value of these indicators was analyzed in estimating prognosis, especially in patients with axillary node-positive breast ca