c-erbB-2 oncoprotein expression in malignant and nonmalignant breast tissue
โ Scribed by A. McCann; P. A. Johnston; P. A. Dervan; W. J. Gullick; D. N. Carney
- Book ID
- 112947177
- Publisher
- Springer-Verlag
- Year
- 1989
- Tongue
- English
- Weight
- 346 KB
- Volume
- 158
- Category
- Article
- ISSN
- 1863-4362
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Ampliยฎcation of the c-erbB2 oncogene and numerical aberrations of chromosome 17 occur in human breast carcinomas. Apocrine adenosis (AA) of the breast has been shown occasionally to have c-erbB2 overexpression and a possible premalignant potential, but little is known about cellular level genetic al
This study was aimed at comparing screen-detected and symptomatic breast carcinomas with regard to the prevalence of positive immunostaining for c-erb-B-2 oncoprotein. Paraffin sections of 8 I breast carcinomas detected through the National Screening Programme were examined for the over-expression o