It is well established that the activation of proto-oncogenes could trigger uncontrolled cell growth and cancer development. Although this correlation has already been evidenced in several human tumors, no conclusive studies have related oncogene activation with the development of prostatic neoplasi
c-erbB-2 oncoprotein expression in primary human tumors
โ Scribed by Amanda McCann; Peter A. Dervan; P. A. Johnston; Desmond N. Carney; William J. Gullick
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 582 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0008-543X
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## Background: The c-erbb-2 gene codes for a putative transmembrane protein, similar in structure to the epidermal growth factor receptor. amplification and/or overexpression of the gene has been recently described with a prognostic significance in a variety of human adenocarcinomas. ## Methods:
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