C 2 -Symmetric Bis-sulfoxide: A Novel Chiral Auxiliary for Asymmetric Desymmetrization of Cyclic m eso -1,2-Diols
β Scribed by Maezaki, Naoyoshi; Sakamoto, Atsunobu; Nagahashi, Noboru; Soejima, Motohiro; Li, Ying-Xia; Imamura, Tsuneaki; Kojima, Naoto; Ohishi, Hirofumi; Sakaguchi, Ken-ichi; Iwata, Chuzo; Tanaka, Tetsuaki
- Book ID
- 127312482
- Publisher
- American Chemical Society
- Year
- 2000
- Tongue
- English
- Weight
- 130 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
A novel C~-symmetric bis-sulfoxide 1 was synthesized as a chiral auxiliary for asymmetric desymmetrization of meso-1,2-diols. cis-Cyclohexane-1,2-dioi and cis-cyclopentane-1,2-diol were desymmetrized via acetalization with I followed by basepromoted acetal cleavage with high diastereoselectivity (>9
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