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Burimamide is a selective inhibitor of thromboxane-A biosynthesis in human platelet microsomes

✍ Scribed by Geoffrey Allan; Kenneth E. Eakins


Book ID
119048617
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
145 KB
Volume
15
Category
Article
ISSN
0090-6980

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The pharmacokinetics and pharmacologic effects of a potent, selective inhibitor of thromboxane synthetase, CV-4151 [(E)-7-phenyl-7-(3-pyridyl)-6-heptenoic acid] on prostanoid formation and platelet aggregation were studied in 42 healthy male volunteers. The drug was well tolerated. After oral admini