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Bumetanide: Radioimmunoassay and pharmacokinetic profile in humans

✍ Scribed by W. R. Dixon; R. L. Young; A. Holazo; M. L. Jack; R. E. Weinfeld; K. Alexander; A. Liebman; S. A. Kaplan


Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
491 KB
Volume
65
Category
Article
ISSN
0022-3549

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In a cross-sectional study of the pharmacokinetics and pharmacodynamics of peroral and intravenous bumetanide (0.5 mg, single dose), total and renal clearance of the diuretic was si~ni6cantly lower in elderly persons than in young adults, resulting in higher bumetanide plasma levels in the aged. Non