Bullous lesions in Bazex syndrome and successful treatment with oral psoralen phototherapy

✍ Scribed by David Gill; Peter Fergin; John Kelly

• Publisher: John Wiley and Sons
• Year: 2001
• Tongue: English
• Weight: 86 KB
• Volume: 42
• Category: Article
• ISSN: 0004-8380
• DOI: 10.1046/j.1440-0960.2001.00535.x

✦ Synopsis

SUMMARY

A 59‐year‐old man presented with a psoriasiform dermatitis with associated bullae and destructive nail dystrophy of the hands and feet. He had lost 10 kg weight over 6 months and a mass in the neck was noted. He was provisionally diagnosed with Bazex syndrome (acrokeratosis paraneoplastica) and subsequent investigations revealed a squamous cell carcinoma in the right piriform fossa. His skin lesions were treated with oral psoralen and ultraviolet A phototherapy and this cleared the cutaneous changes, but the nail changes have persisted at 18 months follow up.