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Successful treatment of the Meige syndrome with oral zolpidem monotherapy

✍ Scribed by Jae Young An; Joong-Seok Kim; Yeong-In Kim; Kwang Soo Lee

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
378 KB
Volume
23
Category
Article
ISSN
0885-3185

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✦ Synopsis

Disease Causing Hereditary Late-Onset Ataxia with Only Minimal White Matter Changes: A Report of Two Sibs ataxia. Additional-yet not obligate-clinical features (palatal tremor, kyphoscoliosis) and more or less distinctive MRI findings (subtle white matter changes, marked atrophy of brainstem, and spinal cord) might constitute clues that hint towards this specific diagnosis.

LEGENDS TO THE VIDEO

Segment 1. Mild ataxic and bouncing gait; note the flexion contractures of the knees; difficulty tandem walking.

Segment 2. Bent-hip and bent-knee posture. Segment 3. Ocular pursuit showing jerky pursuit movements.

Segment 4. Horizontal saccades showing multi-step saccades and ocular dysmetria (both hypometric and hypermetric).

Segment 5. Cerebellar dysarthria on repeating the Dutch sentence ''rode ronde appels rollen van de zoldertrap'' and on repeating ''PATAKA.'' Segment 6. Mild decomposition of movement during finger-to-nose testing.

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Treatment of myelodysplastic syndrome with 2 schedules and doses of oral topotecan : A Randomized Phase 2 Trial by the Cancer and Leukemia Group B (CALGB 19803)
✍ David L. Grinblatt; Daohai Yu; Vera Hars; James W. Vardiman; Bayard L. Powell; S πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 156 KB πŸ‘ 1 views

## Abstract ## BACKGROUD: The Cancer and Leukemia Group B evaluated oral topotecan administered at 2 schedules and doses for myelodysplastic syndrome (MDS). ## METHODS: Patients with previously untreated primary or therapy‐related MDS were eligible. Patients with refractory anemia (RA), RA with