This review summarizes studies on the reciprocal regulation of neuroblastoma neurite outgrowth by thrombin and protease nexin-1 (PN-1). PN-1 recently was shown to possess the same deduced amino acid sequence as the glial-derived neurite-promoting factor. The neurite outgrowth activity of PN-1 depend
β¦ LIBER β¦
BubR1 regulates neurite outgrowth of neuroblastoma cells
β Scribed by Yamagata, Hirotaka; Uchida, Shusaku; Otsuki, Koji; Hobara, Teruyuki; Shibata, Tomohiko; Higuchi, Fumihiro; Abe, Naoko; Watanabe, Yoshifumi
- Book ID
- 122819663
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 120 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0168-0102
No coin nor oath required. For personal study only.
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Protease nexin-1 (PN-1) is a protein proteinase inhibitor recently shown to be identical with the glial-derived neurite-promoting factor or glial-derived nexin. It has been shown to promote neurite outgrowth in neuroblastoma cells and in sympathetic neurons. The present experiments were designed to
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