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Apolipoprotein E4 expression inhibits neurite outgrowth from neuroblastoma cells

✍ Scribed by S. Bellosta; B.P. Nathan; R.W. Mahley; R.E. Pitas


Book ID
119179779
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
155 KB
Volume
31
Category
Article
ISSN
1043-6618

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This review summarizes studies on the reciprocal regulation of neuroblastoma neurite outgrowth by thrombin and protease nexin-1 (PN-1). PN-1 recently was shown to possess the same deduced amino acid sequence as the glial-derived neurite-promoting factor. The neurite outgrowth activity of PN-1 depend