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BsmI vitamin D receptor genotypes influence the efficacy of antiresorptive treatments in postmenopausal osteoporotic women. A 1-year multicenter, randomized and controlled trial

✍ Scribed by Stefano Palomba; Francesco Orio; Tiziana Russo; Angela Falbo; Achille Tolino; Francesco Manguso; Vincenzo Nunziata; Pasquale Mastrantonio; Gaetano Lombardi; Fulvio Zullo

Publisher: Springer-Verlag
Year: 2005
Tongue: English
Weight: 361 KB
Volume: 16
Category: Article
ISSN: 0937-941X
DOI: 10.1007/s00198-004-1800-5

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## Abstract Most osteoporosis drugs act by inhibiting bone resorption. A need exists for osteoporosis therapies that stimulate new bone formation. 2‐Methylene‐19‐nor‐(20__S__)‐1α,25‐dihydroxyvitamin D~3~ (2MD) is a vitamin D analogue that potently stimulates bone formation activity in vitro and in