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The effect of high-dose vitamin D on bone mineral density and bone turnover markers in postmenopausal women with low bone mass—a randomized controlled 1-year trial

✍ Scribed by G. Grimnes; R. Joakimsen; Y. Figenschau; P. A. Torjesen; B. Almås; R. Jorde

Publisher: Springer-Verlag
Year: 2011
Tongue: English
Weight: 320 KB
Volume: 23
Category: Article
ISSN: 0937-941X
DOI: 10.1007/s00198-011-1752-5

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## Abstract Most osteoporosis drugs act by inhibiting bone resorption. A need exists for osteoporosis therapies that stimulate new bone formation. 2‐Methylene‐19‐nor‐(20__S__)‐1α,25‐dihydroxyvitamin D~3~ (2MD) is a vitamin D analogue that potently stimulates bone formation activity in vitro and in