Bronchodilator Activity of Theophylline Derivatives Substituted at the 7-Position
โ Scribed by Stefano Corsano; Rossana Scapicchi; Giovannella Strappaghetti
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 351 KB
- Volume
- 327
- Category
- Article
- ISSN
- 0365-6233
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
I-Substituted te.mcycm. otiho&bmam' meS, ticatalyzed azide rearrangements. 7(or 9)-azimyclines Abstract llwC-8 funcdooalizatiooof te~clinederivatives via acid-catalyzed reatIangemf%It Of 7(or 9)azieyclines is c%zscribed. These ccmpomaaretbefifsttobepreparedfmulanin~ttehacyclincnucleus.
The nucleophilic addition of TMSC(Li)N 2 at the low reactive the nucleophile mainly (methyl, chloromethyl or halogen) or completely (isopropyl) toward the C-5 position. The fine-C-5 position of the uracil ring of C-6 substituted uracil derivatives is reported. The ratio of C-5 versus C-6 tuned subst