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Bromodeoxyuridine mutagenesis, ribonucleotide reductase activity, and deoxyribonucleotide pools in hydroxyurea-resistant mutants

โœ Scribed by Charles R. Ashman; G. Prem Veer Reddy; Richard L. Davidson

Book ID
112558781
Publisher
Springer
Year
1981
Tongue
English
Weight
968 KB
Volume
7
Category
Article
ISSN
1572-9931

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Hydroxyurea-resistant Aedes albopictus mosquito cells were selected by incremental exposure of unmutagenized cells to hydroxyurea concentrations ranging from 0.1 to 8 mM. Clonal populations that had become 40-fold more resistant to hydroxyurea than wild-type cells varied in morphology, and their gro