Six new compounds, characterized by a long unsaturated alkyl chain (nC22), were isolated from a marine sponge. All compounds except for one, possess an enyne terminus on one side of the molecule and either a terminal acetylene (in four) or a propargyl alcohol on the other end. Four of the compounds
Brominated Polyacetylenes from the Philippines Sponge Diplastrella sp.
β Scribed by Lerch, Melissa L.; Harper, Mary Kay; Faulkner, D. John
- Book ID
- 126107367
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 54 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0163-3864
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Four new polyacetylenes (34) with cytotoxic activities against human tumor cell lines (A549, SK-OV-3, SK-MEL-2, XF498, and HCTl5) have been isolated from the marine sponge petMsia sp Th9 were given the trivial names of dideoxypetrosynols A-D.
Six brominated unsaturated polyenynic C , Cl and C -acids have been isolated fron the marine sponge Xestos a ia p ., gollect&t in the straits of the Gulf of Eilat (the Red Sea , M their structure elucidated ) p i 8 by spectroscopic methods. The lH and 13C resrauurce lines of four ccapozmds were full