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Broad-spectrum antiviral activity of PNU-183792, a 4-oxo-dihydroquinoline, against human and animal herpesviruses

โœ Scribed by Roger J. Brideau; Mary L. Knechtel; Audris Huang; Valerie A. Vaillancourt; Ellen E. Vera; Nancee L. Oien; Todd A. Hopkins; Janet L. Wieber; Karen F. Wilkinson; Bob D. Rush; Francis J. Schwende; Michael W. Wathen


Book ID
114144381
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
133 KB
Volume
54
Category
Article
ISSN
0166-3542

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Inhibition of clinical isolates of human
โœ Mary L. Knechtel; Audris Huang; Valerie A. Vaillancourt; Roger J. Brideau ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 53 KB

The susceptibility of human cytomegalovirus (CMV) and varicella zoster virus (VZV) clinical isolates to PNU-183792, a 4-oxo-dihydroquinoline, was examined. The antiviral potency of PNU-183792, a non-nucleoside inhibitor, was compared to the licensed nucleoside inhibitors ganciclovir and acyclovir us