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Broad-spectrum antiviral activity of chebulagic acid and punicalagin against viruses that use glycosaminoglycans for entry

โœ Scribed by Lin, Liang-Tzung; Chen, Ting-Ying; Lin, Song-Chow; Chung, Chueh-Yao; Lin, Ta-Chen; Wang, Guey-Horng; Anderson, Robert; Lin, Chun-Ching; Richardson, Christopher D


Book ID
121628625
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
706 KB
Volume
13
Category
Article
ISSN
1471-2180

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Antiviral activity of arbidol, a broad-s
โœ Megan J. Brooks; Elena I. Burtseva; Philip J. Ellery; Glenn A. Marsh; Andrew M. ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 325 KB

## Abstract The therapeutic activity of arbidol was investigated against representatives of seven different virus families. Its 50% median effective concentration (EC~50~) was 0.22โ€“11.8โ€‰ยตg/ml (0.41โ€“22โ€‰nM). Therapeutic indices of 91 were obtained for type 1 poliovirus and 1.9โ€“8.5 for influenza A and