Brivaracetam: a rational drug discovery success story
โ Scribed by M A Rogawski
- Book ID
- 109839018
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 73 KB
- Volume
- 154
- Category
- Article
- ISSN
- 0007-1188
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract To overcome the problem of high attrition rates in the drug discovery process, an efficient strategy how to identify, select, characterize and validate the most suitable drug targets before embarking on the resourceโintense steps of lead discovery and lead optimization is mandatory. We
The discovery and development of paclitaxel, which covered a time span of some 30 years, has provided some important lessons for those involved in natural product drug discovery and development. These include the adoption of novel screens as they become available, the elucidation of mechanisms of ac