Paclitaxel (Taxol®): A success story wit
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Gordon M. Cragg
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Article
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1998
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John Wiley and Sons
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English
⚖ 204 KB
The discovery and development of paclitaxel, which covered a time span of some 30 years, has provided some important lessons for those involved in natural product drug discovery and development. These include the adoption of novel screens as they become available, the elucidation of mechanisms of ac