Bridged 5,6,7,8-Tetrahydro-1,6-naphthyridines, Analogues of Huperzine A: Synthesis, Modelling Studies and Evaluation as Inhibitors of Acetylcholinesterase
β Scribed by Sofie Vanlaer; Arnout Voet; Constant Gielens; Marc De Maeyer; Frans Compernolle
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 465 KB
- Volume
- 2009
- Category
- Article
- ISSN
- 1434-193X
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## Abstract A new access to 5βphenylβ5,6,7,8βtetrahydroβ1,6βnaphthyridines **25aβ28a** (n=1) and 5βphenylβ6,7,8,9βtetrahydroβ5__H__βpyrido[3,2β__c__]azepines **25bβ28b** (n=2) has been developed by first preparing the functional pyridine moiety followed by intramolecular cyclization forming the par
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