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BREFELDIN A INDUCES p53 -INDEPENDENT APOPTOSIS IN PRIMARY CULTURES OF HUMAN PROSTATIC CANCER CELLS

✍ Scribed by WALLEN, ERIC; SELLERS, ROBERT G.; PEEHL, DONNA M.


Book ID
123210497
Publisher
Lippincott Williams and Wilkins
Year
2000
Tongue
English
Weight
889 KB
Volume
164
Category
Article
ISSN
0022-5347

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## BACKGROUND. Apoptosis is induced by various anticancer agents or radiation through the tumor suppressor gene p53-dependent pathway and is also induced by other factors, including transforming growth factor-PI (TGF-0,). In this study, the authors investigated whether TGF-0, would induce apoptosi