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Sodium butyrate induces P53-independent, Fas-mediated apoptosis in MCF-7 human breast cancer cells

✍ Scribed by Valérie Chopin; Robert-Alain Toillon; Nathalie Jouy; Xuefen Le Bourhis

Book ID
118676641
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
311 KB
Volume
135
Category
Article
ISSN
0007-1188

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## Abstract Rotenone is an inhibitor of the mitochondrial electron transport chain complex I, resulting in the generation of reactive oxygen species (ROS). Rotenone has been shown to display anticancer activity through the induction of apoptosis in various cancer cells. However, the underlying mech