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Breast cancer susceptibility after BRCA1/2: finding the genes and potential practical applications

โœ Scribed by BAJ Ponder, AM Dunning, DF Easton, PDP Pharoah

Book ID
120700214
Publisher
BioMed Central
Year
2006
Tongue
English
Weight
325 KB
Volume
8
Category
Article
ISSN
1465-5411

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Analysis of breast cancer susceptibility
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โœ Pimpicha Patmasiriwat; Kris Bhothisuwan; Olga M. Sinilnikova; Sandrine Chopin; S ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 173 KB ๐Ÿ‘ 2 views

Here we report the study on BRCA1 and BRCA2 mutations in 12 Thai breast and/or ovarian cancer families and 6 early-onset breast or breast/ovarian cancer cases without a family history of cancer. Five distinct rare alterations were identified in each gene: four introducing premature stop codons, one