𝔖 Bobbio Scriptorium
✦   LIBER   ✦

BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells

✍ Scribed by Tassone, P; Tagliaferri, P; Perricelli, A; Blotta, S; Quaresima, B; Martelli, M L; Goel, A; Barbieri, V; Costanzo, F; Boland, C R


Book ID
109997531
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
164 KB
Volume
88
Category
Article
ISSN
0007-0920

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


BRCA1 modulates malignant cell behavior,
✍ Moltira Promkan; Guangming Liu; Pimpicha Patmasiriwat; Subhas Chakrabarty 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 483 KB

## Abstract BRCA1 is a multifunctional tumor‐suppressive protein. Many functional aspects of BRCA1 are not fully understood. We used a shRNA approach to probe the function of BRCA1 in human breast cancer cells. Knocking down BRCA1 expression by shRNA in the wild‐type BRCA1 human breast cancer MCF‐7

Deregulation of cofactor of BRCA1 expres
✍ Jianlong Sun; Gareth Watkins; Ashley L. Blair; Christopher Moskaluk; Sagar Ghosh 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 311 KB

## Abstract Cofactor of BRCA1 (COBRA1) is an integral component of the human negative elongation factor (NELF), a four‐subunit protein complex that inhibits transcription elongation. Previous in vivo work indicates that COBRA1 and the rest of the NELF complex repress estrogen‐dependent transcriptio