✦ LIBER ✦

Brain targeting of anti-HIV nucleosides: synthesis and in vitro and in vivo studies of dihydropyridine derivatives of 3'-azido-2',3'-dideoxyuridine and 3'-azido-3'-deoxythymidine

✍ Scribed by Chu, C. K.; Bhadti, V. S.; Doshi, K. J.; Etse, J. T.; Gallo, J. M.; Boudinot, F. D.; Schinazi, R. F.

Book ID: 125543344
Publisher: American Chemical Society
Year: 1990
Tongue: English
Weight: 727 KB
Volume: 33
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm00170a023

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Interaction of the 5′-phosphates of the

Interaction of the 5′-phosphates of the anti-hiv agents, 3′-azido-3′-deoxythymidine and 3′-azido-2′,3′-dideoxyuridine, with thymidylate synthase

✍ Jolanta M. Dzik; Maria Bretner; Tadeusz Kulikowski; Joanna Ciesla; Jaroslaw M. C 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 380 KB

5-chloro-substituted derivatives of 2',3

5-chloro-substituted derivatives of 2',3'-didehydro-2' ,3'-dideoxyuridine, 3'-fluoro-2' ,3'-dideoxyuridine and 3'-azido-2' ,3'-dideoxyuridine as anti-HIV agents

✍ Jan Balzarini; Arthur Van Aerschot; Piet Herdewijn; Erik De Clercq 📂 Article 📅 1989 🏛 Elsevier Science 🌐 English ⚖ 574 KB

Synthesis and anti-HIV activities of bis

Synthesis and anti-HIV activities of bis-(cycloSaligenyl) pronucleotides derivatives of 3′-fluoro-3′-deoxythymidine and 3′-azido-3′-deoxythymidine

✍ Yousef Ahmadibeni; Rakesh Tiwari; Chelsie Swepson; Jui Pandhare; Chandravanu Das 📂 Article 📅 2011 🏛 Elsevier Science 🌐 French ⚖ 423 KB

Synthesis and Anti-HIV Activity of 5-Alk

Synthesis and Anti-HIV Activity of 5-Alkoxymethyl-3′-azido-2′,3′-dideoxyuridines

✍ Ahmed E.-S. Abdel-Megied; Poul Hansen; Erik B. Pedersen; Claus Nielsen; Carsten 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 453 KB 👁 2 views

## Abstract Methyl 3‐azido‐5‐__O‐tert__‐butyldiphenylsilyl‐2,3‐dideoxy‐D‐__erythro__‐furanoside (3) was coupled with silylated 5‐hydroxymethyluracil (1a) and its C~1~‐C~6~ alkyl ethers 1b–g to give the corresponding protected nucleosides 4a‐g which were deprotected with Bu~4~NF to afford 3‐azido nu

Synthesis and Anti-HIV Activity of β -D-

Synthesis and Anti-HIV Activity of β -D-3′-Azido-2′,3′-unsaturated Nucleosides and β -D-3′-Azido-3′-deoxyribofuranosylnucleosides

✍ Gadthula, Srinivas; Chu, Chung K.; Schinazi, Raymond F. 📂 Article 📅 2005 🏛 Taylor and Francis Group 🌐 English ⚖ 546 KB

An efficient total synthesis of 3′-azido

An efficient total synthesis of 3′-azido-3′-deoxythymidine (AZT) and 3′-azido-2′,3′-dideoxyuridine (AZDDU, CS-87) from D-mannitol

✍ Chung K Chu; J.Warren Beach; Giliyar V Ullas; Yoshiyuki Kosugi 📂 Article 📅 1988 🏛 Elsevier Science 🌐 French ⚖ 231 KB

An efficient stereoselective total synthesis of 3'-azido-3'-deoxythymidine (AZT) and 3'-azido-2',3'-dideoxyuridine (AZDDU, CS-87) from readily available and inexpensive starting material, D-mannitol has been achieved. 3'-Azido-3'-deoxythymidine (AZT) has been found to be a potent antiviral agent ag