A convenient synthesis of 2′,3′-dideoxyi
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I. Victor Ekhato; Jay K. Rinehart
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Article
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2010
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John Wiley and Sons
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French
⚖ 191 KB
## Abstract 2′,3′‐Dideoxyinosine‐^13^C~5~ (ddI‐^13^C~5~) and the related 2′,3′‐dideoxyadenosine‐^13^C~5~ (ddA‐^13^C~5~) were prepared from (S)‐5‐[^13^C~5~]2,3‐dideoxyribonolactone 1. From a batch of this starting material ddI‐^13^C~5~ was made in 27% overall yield in seven steps and ddA‐^13^C~5~ in