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Brain region-dependent increases in β-amyloid and apolipoprotein E levels in hypercholesterolemic rabbits

✍ Scribed by C.-W. Wu; P.-C. Liao; C. Lin; C.-J. Kuo; S.-T. Chen; H.-I. Chen; Y.-M. Kuo


Publisher
Springer
Year
2003
Tongue
English
Weight
168 KB
Volume
110
Category
Article
ISSN
1435-1463

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## Abstract Elevations in β‐amyloid peptide (Aβ) levels after traumatic brain injury (TBI) may confer risk for developing Alzheimer's disease in head trauma patients. We investigated the effects of simvastatin, a 3‐hydroxy‐3‐methylglutaryl‐CoA reductase inhibitor, on hippocampal Aβ burden in a clin