Brain Pharmacokinetics and Tissue Distribution In Vivo of Fluvoxamine and Fluoxetine by Fluorine Magnetic Resonance Spectroscopy
✍ Scribed by Nicolas R Bolo; Yann Hodé; Jean-François Nédélec; Eric Lainé; Gabrielle Wagner; Jean-Paul Macher
- Book ID
- 114280658
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 637 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1470-634X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Low-field in vivo electron spin resonance (ESR) has been used to follow the course of metabolism and distribution of a paramagnetic spin probe, 3-carboxamido-2,2,5,5tetramethylpyrrolidine-I-oxyl. Sprague-Dawley rats (250-300 g) were catheterized in the jugular vein and given serial doses ofthe nitro
Proton magnetic resonance spectroscopy ( 1 H MRS) has the potential to provide a noninvasive assessment of hepatic lipid composition. The spectral resolution of in vivo clinical MR data is currently limited by the magnetic field strengths available and by motion artifact. Therefore, interpretation o
## Abstract The therapeutic mechanism of action of lithium (Li) in bipolar disorder is unknown. While Li is presumed to work intracellularly in the brain, the fraction of intracellular Li in the brain in vivo is not known. It has not yet been possible to determine, directly and noninvasively, the i