Brain iron accumulation in dysmetabolic iron overload syndrome with restless legs syndrome
✍ Scribed by Lillo-Triguero, Laura; Del Castillo, Alejandro; Morán-Jiménez, María-José; Guzmán-De Villoria, Juan A.; Guillem, Amparo; Peraita-Adrados, Rosa
- Book ID
- 122130381
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 275 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1389-9457
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## Abstract Evidence for tissue iron deficiency in restless legs syndrome (RLS) is limited to the substantia nigra (SN). Using MRI, we assessed T2 values of various brain regions in 6 RLS patients and 19 controls and correlated them with sonographically assessed SN echogenicity. Both neuroimaging f
[edited By] Wayne A. Hening ... [et Al.]. Title From Homepage (viewed Apr. 6, 2010). Includes Bibliographical References And Index. Mode Of Access: World Wide Web.
The impressive relief from restless legs syndrome (RLS) symptoms provided by levodopa treatment indicates RLS is caused by a dopaminergic abnormality. But similar and more lasting relief also occurs for iron treatment in some patients. Thus there are two major putative causes for RLS: CNS dopaminerg