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Brain injury caused by HIV protease inhibitors: Role of lipodystrophy and insulin resistance

✍ Scribed by Sunita Gupta; Alecia G. Knight; Boriss Y. Losso; Donald K. Ingram; Jeffrey N. Keller; Annadora J. Bruce-Keller


Book ID
113458826
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
889 KB
Volume
95
Category
Article
ISSN
0166-3542

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## Abstract Protease inhibitor (PI) therapy for the treatment of patients infected with human immunodeficiency virus is frequently associated with insulin resistance and diabetic complications. These adverse effects of PI treatment result to a large extent from their inhibition of insulin‐stimulate