Brain-derived neurotrophic factor and neurotrophin-4 increase neurotrophin-3 expression in the rat hippocampus
✍ Scribed by Dan Lindholm; Maria da Penha Berzaghi; Jonathan Cooper; Hans Thoenen; Eero Castrén
- Book ID
- 116150842
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 844 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0736-5748
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Levels of brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT3) mRNA expression were measured in a rodent model of traumatic brain injury (TBI) following unilateral injury to the cerebral cortex. To obtain reliable data on the co-expression of neurotrophin genes, adjacent coronal section
Neurotrophins, including nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-3 (NT-3), are critical for the maintenance and plasticity of central nervous system (CNS) neurons. We tested the hypothesis that cortical neurons participate in redundant autocrine/paracrin