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Brain bioavailability of human intravenous immunoglobulin and its transport through the murine blood–brain barrier

✍ Scribed by St-Amour, Isabelle; Paré, Isabelle; Alata, Wael; Coulombe, Katherine; Ringuette-Goulet, Cassandra; Drouin-Ouellet, Janelle; Vandal, Milène; Soulet, Denis; Bazin, Renée; Calon, Frédéric

Book ID
124167436
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
673 KB
Volume
33
Category
Article
ISSN
0271-678X

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✍ W. M. Pardridge 📂 Article 📅 1981 🏛 Springer 🌐 English ⚖ 971 KB

An understanding of the mechanisms of transport of circulating nutrients and hormones through the brain capillary wall, i. e., the blood-brain barrier, is important because the availability in brain of these substances influences a number of cerebral metabolic pathways. For example, the utilization