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BRAFV600Emutation in Turkish patients with papillary thyroid cancer: strong correlation with indicators of tumor aggressiveness

✍ Scribed by Kurtulmus, Neslihan; Duren, Mete; Ince, Umit; Cengiz Yakicier, M.; Peker, Onder; Aydın, Ozlem; Altiok, Ender; Giray, Serdar; Azizlerli, Halil


Book ID
118820971
Publisher
Springer
Year
2012
Tongue
English
Weight
228 KB
Volume
42
Category
Article
ISSN
0969-711X

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## Abstract The role of aberrant tumor suppressor gene methylation in the aggressiveness of papillary thyroid cancer (PTC) has not been documented. By showing promoter methylation‐induced gene silencing in PTC‐derived cell lines, we first demonstrated the functional consequence of methylation of se