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BRAFV600EMutation is Associated with Tumor Aggressiveness in Papillary Thyroid Cancer

✍ Scribed by Su-jin Kim; Kyu Eun Lee; Jun Pyo Myong; Jeong-hwan Park; Yoon Kyung Jeon; Hye Sook Min; So Yeon Park; Kyeong Cheon Jung; Do Hoon Koo; Yeo-Kyu Youn


Book ID
105981959
Publisher
Springer
Year
2011
Tongue
English
Weight
217 KB
Volume
36
Category
Article
ISSN
0364-2313

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## Abstract The role of aberrant tumor suppressor gene methylation in the aggressiveness of papillary thyroid cancer (PTC) has not been documented. By showing promoter methylation‐induced gene silencing in PTC‐derived cell lines, we first demonstrated the functional consequence of methylation of se