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BPDE-INDUCED LYMPHOCYTIC CHROMOSOME 3p DELETIONS MAY PREDICT RENAL CELL CARCINOMA RISK

✍ Scribed by Horikawa, Yohei; Zhu, Yimin; Yang, Hushan; Wood, Christopher G; Wu, Xifeng

Book ID
123285824
Publisher
Lippincott Williams and Wilkins
Year
2008
Tongue
English
Weight
158 KB
Volume
179
Category
Article
ISSN
0022-5347

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## Background: Tobacco exposure is an established risk factor for head and neck squamous cell carcinoma (hnscc). benzo[alpha]pyrene diol expoxide (bpde), a main metabolic product of the tobacco smoke constituent benzo[alpha]pyrene, induces chromosomal aberrations at specific loci. chromosomal aberr