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Botulinum toxin and cerebral palsy: time for reflection?

✍ Scribed by M Gough; C Fairhurst; A P Shortland


Book ID
111130152
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
70 KB
Volume
47
Category
Article
ISSN
0012-1622

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Local injection of botulinum toxin (BT) is a wellestablished treatment option for spastic movement disorders in children. BT blocks the release of acetylcholine from the axon terminal into the synaptic cleft of the motor endplate resulting in paresis of the injected musculature. Such localised, temp