This study evaluated the effects of multilevel botulinum toxin type A (BTXβA) treatments on the gait pattern of children with spastic cerebral palsy (Gross Motor Function Classification System Levels IβIII). In this nested caseβcontrol design, 30 children (mean age 6y 11mo [SD 1y 5mo]; 21 males, nin
Botulinum toxin in children with cerebral palsy
β Scribed by Pratibha Singhi; Munni Ray
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 517 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0019-5456
No coin nor oath required. For personal study only.
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The objective was to determine the effects of low-dose, highconcentration, dual localized botulinum toxin A (BTX-A) injections on upper limb movement quality and function. Study design was an evaluator-blinded, randomized, controlled trial. Forty-two children (31 males, 11 females; range 2-8y, mean
Local injection of botulinum toxin (BT) is a wellestablished treatment option for spastic movement disorders in children. BT blocks the release of acetylcholine from the axon terminal into the synaptic cleft of the motor endplate resulting in paresis of the injected musculature. Such localised, temp